

Before she began work on it, Mukerji trained at Roshan Taneja's acting institute. Mukerji accepted the role due to her mother's insistence that she continue to pursue acting on an experimental basis. Soon after, Khan approached her with another film offer to play the leading role in the social drama Raja Ki Aayegi Baraat, after Mamta Kulkarni refused the offer.

At age 18, Mukerji experimented with acting by playing the leading role in her father's Bengali film Biyer Phool (1996). Her father disapproved of a full-time career in film at such a young age, so she rejected the offer. In 1994, director Salim Khan approached Mukerji to play the lead female role in his directorial, Aa Gale Lag Jaa. Mukerji, a practising Hindu, takes part in the festivities with her entire family. As part of an annual tradition, the Mukherjee family celebrates the festival of Durga Puja in the suburban neighbourhood of Santacruz every year. She is a trained Odissi dancer and began learning the dance form while in the tenth grade. Mukerji received her education at Maneckji Cooper High School in Juhu and graduated with a degree in Home Science from SNDT Women's University. She said, "There were already too many actresses at home and I wanted to be someone different". Despite her parents and most of her relatives being members of the Indian film industry, Mukerji was uninterested in pursuing a career in film. Another paternal cousin, Ayan Mukerji, is a scriptwriter and film director. Her maternal aunt, Debashree Roy, is a Bengali film actress and her paternal cousin, Kajol, is a Hindi film actress and her contemporary. Her elder brother, Raja Mukherjee, is a film producer and director. Her mother, Krishna Mukherjee, is a former playback singer. Her father, Ram Mukherjee (born to the Mukherjee-Samarth family), is a former film director and one of the founders of Filmalaya Studios. Mukerji was born in Calcutta (present-day Kolkata) on 21 March 1978.

Mukerji is married to filmmaker Aditya Chopra, with whom she has a daughter. She has participated in concert tours and stage shows, and featured as a talent judge for the 2009 reality show Dance Premier League. Mukerji is involved with humanitarian causes and is vocal about issues faced by women and children. The lattermost emerged as her highest-grossing release. This changed when she played a headstrong journalist in the thriller No One Killed Jessica (2011), and further success came for her starring roles in the thrillers Talaash: The Answer Lies Within (2012), Mardaani (2014) and its sequel Mardaani 2 (2019), and the comedy-drama Hichki (2018). Mukerji then collaborated with Yash Raj Films on several unsuccessful films which led critics to bemoan her choice of roles. She also gained praise for playing an abused wife in the political thriller Yuva (2004), a deaf and blind woman in the drama Black (2005) and a Rajasthani bride in the female-led fantasy Paheli (2005). Mukerji established herself by starring in several commercially successful romantic films, including Chalte Chalte (2003), Hum Tum (2004), Veer-Zaara (2004), and Kabhi Alvida Naa Kehna (2006), and the crime comedy Bunty Aur Babli (2005).

Following a brief setback, the year 2002 marked a turning point for her when she was cast by Yash Raj Films as the star of the drama Saathiya. Mukerji had her first commercial success with the action film Ghulam (1998) and breakthrough with the romance Kuch Kuch Hota Hai (1998). As a teenager she dabbled with acting by starring in her father Ram Mukherjee's Bengali-language film Biyer Phool and in the social drama Raja Ki Aayegi Baraat (both 1996). Īlthough Mukerji was born into the Mukherjee-Samarth family, in which her parents and relatives were members of the Indian film industry, she did not aspire to pursue a career in film. Mukerji has featured in listings of the most popular and highest-paid actresses of the 2000s. A recipient of multiple accolades, including seven Filmfare Awards, her roles have been cited in the media as a significant departure from previous screen portrayals of Indian women. Rani Mukerji (pronounced born 21 March 1978) is an Indian actress who works in Hindi films.
